Cast of Frasier

Kelsey Grammer portrayed the titular character of Frasier Crane, a radio psychiatrist with a quick wit and refined tastes. Frasier is known for his sophisticated demeanor, love of opera, and his complicated relationships with his family members and friends.

David Hyde Pierce played the role of Niles Crane, Frasier's younger brother. Niles is a fellow psychiatrist who shares his brother's love of intellectual pursuits and often finds himself in humorous situations. His unrequited love for Daphne Moon provides a running storyline throughout the series.

Jane Leeves portrayed Daphne Moon, the live-in housekeeper for the Crane family. Daphne hails from Manchester, England, and is known for her psychic abilities and quirky personality. As the series progresses, she becomes an integral part of the Crane family.

Peri Gilpin played Roz Doyle, Frasier's radio show producer and close friend. Roz is a strong, independent woman with a sharp sense of humor. She often provides a grounding presence among the eccentric characters of the show.

John Mahoney portrayed Martin Crane, Frasier and Niles' father. Martin is a retired police officer with a no-nonsense attitude and a love for his recliner. His dynamic with his sons, particularly Frasier, forms a central part of the show's storyline.

Sherry Lansing provided the voice for Angela, Frasier's persistent but never-seen agent. Angela is a no-nonsense professional who is often at odds with Frasier's extravagant personality and demands.

Cyd Charisse provided the voice for Polly, Frasier's unseen but often-discussed date and love interest. Polly's mysterious and glamorous persona adds an element of intrigue to Frasier's love life.

John LaMotta played Duke, a regular character at the Café Nervosa where Frasier and his friends often meet. Duke is known for his dry humor and cynical outlook on life.