Family Guy (TV) Cast
The cast of Family Guy. Updated on October 2, 2025.
761 actors
Seth MacFarlane
as Peter Griffin / Brian Griffin / Stewie Griffin / Glenn Quagmire / Tom Tucker (voice) (424 episodes)

Seth MacFarlane is the creator of Family Guy and provides the voices for several main characters on the show. He voices Peter Griffin, the bumbling yet well-meaning father of the Griffin family. Seth MacFarlane also provides the voice for Brian Griffin, the sophisticated and often sarcastic family pet. Additionally, he voices Stewie Griffin, the intelligent but devious baby of the family. MacFarlane also lends his voice to Glenn Quagmire, the overly sex-obsessed neighbor of the Griffins, as well as Tom Tucker, the news anchor at the local Quahog news station.

Alex Borstein
as Lois Griffin / Tricia Takanawa / Loretta Brown / Barbara Pewterschmidt (voice) (424 episodes)

Alex Borstein provides the voices for several important female characters on Family Guy. She voices Lois Griffin, the patient and supportive wife of Peter Griffin. Borstein also voices Tricia Takanawa, a news anchor at the Quahog news station. Additionally, she provides the voices for Loretta Brown, the former wife of Cleveland Brown, and Barbara Pewterschmidt, Lois's wealthy and overbearing mother.

Mila Kunis
as Meg Griffin (voice) (416 episodes)

Mila Kunis voices Meg Griffin, the socially awkward and often overlooked daughter of the Griffin family. Despite facing constant ridicule and mistreatment from her family and peers, Meg remains resilient and tries to find her place in the world.

Seth Green
as Chris Griffin (voice) (424 episodes)

Seth Green provides the voice for Chris Griffin, the overweight and not-so-bright son of the Griffin family. Chris is known for his innocent nature and his love for food. Green brings comedic timing and a unique voice to the character.

Waylon Jennings
as Waylon Jennings (voice) (2 episodes)

Waylon Jennings lends his voice to the character of Waylon Jennings, a fictional version of himself on the show. The character appears as a hallucination or spiritual figure and provides guidance to certain characters in the form of country music.

Mary Kay Bergman
as Sherry (voice) (2 episodes)

Mary Kay Bergman provided the voice for Sherry in the early seasons of Family Guy. Sherry is a minor character who appeared in a few episodes of the show.

Ray Liotta
as Zack (voice) (1 episode)

Ray Liotta provides the voice for Zack, a character who appears in a few episodes of Family Guy. Zack is a friend of Stewie Griffin and engages in various adventures with him.

Abe Vigoda
as Abe Vigoda (voice) (1 episode)

Abe Vigoda provides the voice for himself in a guest appearance on Family Guy. Vigoda is a well-known actor and his cameo on the show adds a touch of celebrity presence to the episode in which he appears.

Peter Frampton
as Peter Frampton (voice) (1 episode)
Peter Gallagher
as Jared (voice) (1 episode)
Ace Frehley
as Ace Frehley (voice) (1 episode)
Betty White
as Betty White (voice) (1 episode)
Cloris Leachman
as Cloris Leachman (voice) (2 episodes)
JoAnna Garcia
as Liddane (voice) (2 episodes)
Wallace Shawn
as Bertram (voice) (3 episodes)
Judith Light
as Judith Light (voice) (1 episode)
Tom Kenny
as SpongeBob SquarePants (archive sound) (uncredited) (1 episode)
Hugh Hefner
as Hugh Hefner (voice) (2 episodes)
Bill Engvall
as Duke Dillon (voice) (1 episode)
Andy Dick
as Andy Dick (voice) (2 episodes)
George Wendt
as Norm Peterson (voice) (2 episodes)
Seth Rogen
as Seth Rogen (voice) (2 episodes)
Daniel Stern
as Narrator (voice) (1 episode)
Brittany Snow
as Candy (voice) (1 episode)
Dan Aykroyd
as Dan Aykroyd (voice) (1 episode)
Elijah Wood
as Elijah Wood (voice) (1 episode)
Alan Tudyk
as (voice) (1 episode)
Missi Pyle
as Kitty Hawk Woman (voice) (1 episode)
Michelle Kwan
as Michelle Kwan (voice) (2 episodes)
Jon Cryer
as Kevin (voice) (2 episodes)
Bob Barker
as Bob Barker (voice) (3 episodes)
Brian Tochi
as Asian Police Pilot (voice) (2 episodes)
Garrett Morris
as Garrett Morris (2 episodes)
Don Most
as Donny Most (voice) (2 episodes)
Dakota Fanning
as Little Girl (voice) (1 episode)
Martin Mull
as Mr. Harris (voice) (1 episode)
Cynthia Watros
as Security System (voice) (1 episode)
June Foray
as Rocket J. Squirrel (voice) (1 episode)
Jennifer Love Hewitt
as Jennifer Love Hewitt (voice) (1 episode)
A.J. Benza
as A.J. Benza (voice) (1 episode)
Tom Bosley
as Howard Cunningham (voice) (1 episode)
Regis Philbin
as Regis Philbin (voice) (1 episode)
Ben Stein
as Rabbi Goldberg (voice) (3 episodes)
Gina Gershon
as Policewoman (voice) (1 episode)
Ricardo Montalban
as The Cow (voice) (1 episode)
David Cross
as Jerry Kirkwood (voice) (1 episode)
Tori Spelling
as Donna (voice) (1 episode)
Bruce Willis
as Officer John McClane (archive footage) (1 episode)
Louis Gossett Jr.
as Drill Sargent (voice) (1 episode)
Jamie Farr
as Jamie Farr (voice) (1 episode)
Pat Crawford Brown
as Lead Sanka Dancer (voice) (1 episode)
Amanda Bynes
as Anna (voice) (1 episode)
Brian Blessed
as Prince Vultan (voice) (1 episode)
Wentworth Miller
as Jock #4 / Popular Kid #2 (voice) (1 episode)
John O'Hurley
as Cult Leader (voice) (1 episode)
Fairuza Balk
as Connie D'Amico (voice) (2 episodes)
Jenna Jameson
as Jenna Jameson (voice) (1 episode)
Josh Peck
as Charlie (voice) (uncredited) (1 episode)
Estelle Harris
as Death's Mother (voice) (1 episode)
Fred Willard
as Dave Campbell (voice) (2 episodes)
Maurice LaMarche
as Ralph Kramden (voice) (2 episodes)
Robert Downey Jr.
as Patrick Pewterschmidt (voice) (2 episodes)
Carol Channing
as Carol Channing (voice) (1 episode)
Paula Abdul
as Paula Abdul (voice) (2 episodes)
Mark Borchardt
as Mark Borchardt (1 episode)
Denise Crosby
as Denise Crosby (voice) (1 episode)
Arianna Huffington
as Arianna Huffington (voice) (1 episode)
Rainn Wilson
as Dwight Schrute (voice) (1 episode)
Bob Gunton
as Warden (voice) (1 episode)
Joel David Moore
as Jake Sully (voice) (1 episode)
Dick Van Patten
as Tom Bradford (voice) (2 episodes)
Luke Perry
as Luke Perry (voice) (2 episodes)
Ed Asner
as Steve Bellows (voice) (2 episodes)
Mark Hamill
as Luke Skywalker / Obi-Wan Kenobi (voice) (2 episodes)
Kate Rigg
as Brandi / Esperanza (voice) (2 episodes)
Keith Olbermann
as Bob Grossbeard (voice) (2 episodes)
Johnny Galecki
as Leonard Hofstadter (voice) (1 episode)
Lee Majors
as Lee Majors (voice) (1 episode)
Tony Danza
as Tony Danza (voice) (1 episode)
Bruce Lanoil
as (voice) (1 episode)
Frank Welker
as Megatron (voice) (1 episode)
Charles Durning
as Francis Griffin (voice) (6 episodes)
Majel Barrett
as Ship Computer (voice) (1 episode)
Kelly Ripa
as Kelly Ripa (voice) (1 episode)
Jason Priestley
as (voice) (1 episode)
Johnny Knoxville
as Johnny Knoxville (voice) (1 episode)
Perez Hilton
as Perez Hilton (voice) (uncredited) (1 episode)
Michele Lee
as Estelle Lewis (voice) (1 episode)
Nina Dobrev
as Lois' High School Bully (voice) (1 episode)
Aaron Lustig
as Various (voice) (1 episode)
Ron Jeremy
as Ron Jeremy (voice) (1 episode)
Alyssa Milano
as Alyssa Milano (2 episodes)
Laura Silverman
as Amy (voice) (1 episode)
Paul Stanley
as Paul Stanley (voice) (2 episodes)
Tom Brady
as Tom Brady (voice) (1 episode)
Hillary Tuck
as Patty / Girl in Blind Date / Cecilia (voice) (2 episodes)
Michael Bell
as Allstar Seaworthy (voice) (1 episode)
Debbie Reynolds
as Mrs. Wilson (voice) (1 episode)
Brent Spiner
as Brent Spiner (voice) (1 episode)
Craig Ferguson
as Craig Ferguson (1 episode)
For the best insights and data about the TV show Family Guy, visit our main Family Guy page.