Dennis Quaid plays Jerry Lee Lewis, a talented and controversial rock and roll musician known for his dynamic performances and personal scandals.
Winona Ryder portrays Myra Gale Brown, the cousin of Jerry Lee Lewis who controversially becomes his wife at a young age.
John Doe takes on the role of J.W. Brown, Myra Gale Brown's father, who initially disapproves of her relationship with Jerry Lee Lewis.
Stephen Tobolowsky plays Jud Phillips, a record producer who is instrumental in Jerry Lee Lewis' early career.
Alec Baldwin portrays Jimmy Swaggart, a prominent televangelist and cousin of Jerry Lee Lewis who becomes embroiled in a scandal with Lewis.
Lisa Blount appears as Lois Brown, the mother of Myra Gale Brown and a key figure in the unfolding drama surrounding Jerry Lee Lewis.
Trey Wilson takes on the role of Sam Phillips, the legendary record producer and founder of Sun Records who discovers Jerry Lee Lewis.
Steve Allen makes a cameo appearance as himself, a renowned television personality and host who interviews Jerry Lee Lewis.
Michael St. Gerard portrays Elvis Presley, the iconic rock and roll star who shares a tumultuous friendship and rivalry with Jerry Lee Lewis.
Mojo Nixon plays James Van Eaton, a drummer and part of Jerry Lee Lewis' band who contributes to his unique and energetic sound.
Kelli Clevenger appears as a Dancer in an uncredited role, adding to the vibrant atmosphere of the music scenes in the film.
Joshua Sheffield portrays Rusty Brown, a member of Jerry Lee Lewis' family who becomes entangled in the personal and professional turmoil surrounding the musician.
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