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Desus & Mero
Cast
107 cast members · 97 with popularity data
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Episode Ratings
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Full Cast
Sorted by Buzz Score · April 29, 2026
1
Charlize Theron
Self - Illustrious Guest
· 1 eps
42.8
#14 overall
2
Zendaya
Self
· 1 eps
21.8
#45 overall
3
Seth Rogen
Self - Illustrious Guest
· 2 eps
20.9
#50 overall
4
Barack Obama
Self - Illustrious Guest
· 1 eps
14.4
#97 overall
5
Joe Biden
Self - Illustrious Guest
· 1 eps
9.1
#207 overall
6
Jordan Peele
Self - Illustrious Guest
· 1 eps
7.2
#320 overall
7
Ben Stiller
Self - Illustrious Guest
· 1 eps
7.0
#334 overall
8
Anthony Mackie
Self
· 1 eps
6.1
#414 overall
9
Katie Porter
Self - Illustrious Guest
· 1 eps
6.0
#423 overall
10
RZA
Self - Illustrious Guest
· 1 eps
5.5
#516 overall
11
Nick Kroll
Self - Illustrious Guest
· 1 eps
4.8
#652 overall
12
Eddie Murphy
Self
· 1 eps
4.7
#675 overall
13
Amy Poehler
Self - Illustrious Guest
· 1 eps
4.7
#693 overall
14
Jon Stewart
Self - Illustrious Guest
· 1 eps
4.7
#695 overall
15
Demi Lovato
Self
· 1 eps
4.6
#716 overall
16
Yahya Abdul-Mateen II
Self - Illustrious Guest
· 1 eps
4.5
#742 overall
17
Kamala Harris
Self - Illustrious Guest
· 1 eps
4.5
#747 overall
18
Rashida Jones
Self - Illustrious Guest
· 1 eps
4.2
#835 overall
19
LL Cool J
Self - Illustrious Guest
· 1 eps
4.2
#844 overall
20
Ethan Hawke
Self - Illustrious Guest
· 1 eps
4.1
#894 overall
21
Judd Apatow
Self - Illustrious Guest
· 1 eps
3.9
#997 overall
22
Ramy Youssef
Self
· 1 eps
3.8
#1,001 overall
23
Glenn Close
Self
· 1 eps
3.2
#1,334 overall
24
Anna Kendrick
Self - Illustrious Guest
· 1 eps
3.2
#1,345 overall
25
Penn Badgley
Self - Illustrious Guest
· 1 eps
3.2
#1,367 overall
26
Usain Bolt
Self - Illustrious Guest
· 1 eps
3.1
#1,397 overall
27
Spike Jonze
Self - Illustrious Guest
· 1 eps
3.0
#1,485 overall
28
John Mulaney
Self - Illustrious Guest
· 1 eps
3.0
#1,507 overall
29
Whoopi Goldberg
Self
· 1 eps
2.9
#1,611 overall
30
Andy Samberg
Self - Illustrious Guest
· 1 eps
2.8
#1,624 overall
31
Jay Ellis
Self - Illustrious Guest
· 1 eps
2.7
#1,721 overall
32
Jason Derulo
Self - Illustrious Guest
· 1 eps
2.7
#1,744 overall
33
Bill Hader
Self - Illustrious Guest
· 1 eps
2.6
#1,845 overall
34
Dwyane Wade
Self - Illustrious Guest
· 1 eps
2.6
#1,862 overall
35
Mark Cuban
Self - Illustrious Guest
· 1 eps
2.5
#2,011 overall
36
Anthony Fauci
Self - Illustrious Guest
· 1 eps
2.4
#2,049 overall
37
Alicia Keys
Self - Illustrious Guest
· 1 eps
2.4
#2,105 overall
38
Stephen A. Smith
Self - Illustrious Guest
· 1 eps
2.4
#2,108 overall
39
Spike Lee
Self - Illustrious Guest
· 1 eps
2.4
#2,121 overall
40
Tracee Ellis Ross
Self - Illustrious Guest
· 1 eps
2.3
#2,183 overall
41
Carmelo Anthony
Self - Illustrious Guest
· 1 eps
2.2
#2,318 overall
42
Don Cheadle
Self - Illustrious Guest
· 2 eps
2.2
#2,356 overall
43
Lupita Nyong'o
Self - Illustrious Guest
· 1 eps
2.2
#2,435 overall
44
Chris Rock
Self - Illustrious Guest
· 1 eps
2.1
#2,549 overall
45
Gabrielle Union
Self - Illustrious Guest
· 2 eps
2.1
#2,566 overall
46
Tony Hawk
Self - Illustrious Guest
· 1 eps
2.1
#2,569 overall
47
Jaden Smith
Self - Illustrious Guest
· 1 eps
1.9
#2,797 overall
48
John David Washington
Self
· 1 eps
1.8
#2,979 overall
49
Cory Booker
Self - Illustrious Guest
· 1 eps
1.8
#3,086 overall
50
Diplo
Self
· 1 eps
1.8
#3,121 overall
51
Phoebe Bridgers
Self
· 1 eps
1.8
#3,123 overall
52
David Letterman
Self - Illustrious Guest
· 1 eps
1.8
#3,131 overall
53
Delroy Lindo
Self
· 1 eps
1.6
#3,400 overall
54
John Legend
Self - Illustrious Guest
· 2 eps
1.6
#3,478 overall
55
Janelle Monáe
Self - Illustrious Guest
· 1 eps
1.5
#3,687 overall
56
Jesse Williams
Self - Illustrious Guest
· 1 eps
1.5
#3,691 overall
57
Eric André
Self - Illustrious Guest
· 1 eps
1.5
#3,738 overall
58
Ludacris
Self
· 1 eps
1.4
#3,907 overall
59
Kenan Thompson
Self
· 1 eps
1.4
#3,967 overall
60
LaKeith Stanfield
Self - Illustrious Guest
· 1 eps
1.4
#4,125 overall
61
Vince Staples
Self - Illustrious Guest
· 1 eps
1.3
#4,367 overall
62
Lil Nas X
Self - Illustrious Guest
· 1 eps
1.3
#4,467 overall
63
Seth Meyers
Self - Illustrious Guest
· 1 eps
1.3
#4,556 overall
64
Timbaland
Self - Illustrious Guest
· 1 eps
1.2
#4,753 overall
65
Missy Elliott
Self - Illustrious Guest
· 1 eps
1.2
#4,793 overall
66
Kelly Rowland
Self
· 1 eps
1.2
#4,880 overall
67
Issa Rae
Self - Illustrious Guest
· 2 eps
1.0
#5,559 overall
68
Busta Rhymes
Self
· 1 eps
1.0
#5,572 overall
69
Big Sean
Self - Illustrious Guest
· 1 eps
1.0
#5,682 overall
70
Sheila E.
Self
· 1 eps
1.0
#5,942 overall
71
Maxine Waters
Self - Illustrious Guest
· 1 eps
0.9
#6,526 overall
72
Swizz Beatz
Self - Illustrious Guest
· 1 eps
0.9
#6,530 overall
73
Sue Bird
Self - Illustrious Guest
· 1 eps
0.8
#7,106 overall
74
Stacey Abrams
Self - Illustrious Guest
· 2 eps
0.8
#7,131 overall
75
2 Chainz
Self - Illustrious Guest
· 1 eps
0.7
#7,467 overall
76
Kirsten Gillibrand
Self - Illustrious Guest
· 1 eps
0.7
#7,749 overall
77
Malcolm Gladwell
Self - Illustrious Guest
· 1 eps
0.7
#7,985 overall
78
Billy Porter
Self - Illustrious Guest
· 1 eps
0.7
#8,107 overall
79
Eddie Huang
Self
· 1 eps
0.7
#8,141 overall
80
Winston Duke
Self - Illustrious Guest
· 1 eps
0.7
#8,229 overall
81
Matt Walsh
Self - Illustrious Guest
· 1 eps
0.6
#8,574 overall
82
Darrell Wallace, Jr.
Self - Illustrious Guest
· 1 eps
0.6
#9,048 overall
83
J Balvin
Self
· 1 eps
0.6
#9,087 overall
84
Paul Scheer
Self - Special Appearance
· 1 eps
0.6
#9,557 overall
85
Cori Bush
Self - Illustrious Guest
· 1 eps
0.5
#10,588 overall
86
Killer Mike
Self - Illustrious Guest
· 1 eps
0.5
#11,018 overall
87
Andra Day
Self
· 1 eps
0.4
#12,776 overall
88
Ava DuVernay
Self - Illustrious Guest
· 1 eps
0.3
#13,933 overall
89
Jamaal Bowman
Self - Illustrious Guest
· 1 eps
0.3
#14,981 overall
90
Jazmine Sullivan
Self
· 1 eps
0.2
#16,903 overall
91
A$AP Ferg
Self
· 1 eps
0.2
#17,778 overall
92
Sarah Cooper
Self - Illustrious Guest
· 1 eps
0.2
#20,117 overall
93
The Kid Mero
Self - Host
· 180 eps
0.2
#20,662 overall
94
24kGoldn
Self
· 1 eps
0.1
#22,040 overall
95
Travis "Taco" Bennett
Self
· 1 eps
0.1
#22,341 overall
96
Alison Roman
Self - Illustrious Guest
· 1 eps
0.1
#30,020 overall
97
Travon Free
Self
· 1 eps
0.0
#47,326 overall
98
Desus Nice
Self - Host
· 180 eps
—
99
Jaime Harrison
Self - Illustrious Guest
· 1 eps
—
100
Freddie Gibbs
Self
· 2 eps
—
Load full cast (107)
Desus & Mero Stats
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