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My Sister's Keeper
Cast
36 cast members · 20 with popularity data
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Sorted by Buzz Score · April 30, 2026
1
Alec Baldwin
Campbell Alexander
4.5
#734 overall
2
Cameron Diaz
Sara Fitzgerald
4.4
#799 overall
3
Emily Deschanel
Dr. Farquad
3.5
#1,142 overall
4
Joan Cusack
Judge De Salvo
1.9
#2,840 overall
5
Abigail Breslin
Andromeda "Anna" Fitzgerald
1.8
#2,972 overall
6
Jason Patric
Brian Fitzgerald
1.4
#4,067 overall
7
Rick Salomon
Bailiff Bert
1.1
#5,047 overall
8
E. G. Daily
Nurse Susan
1.0
#5,636 overall
9
Mary Jo Deschanel
Saleswoman
0.8
#7,245 overall
10
Lin Shaye
Nurse Adele
0.7
#8,069 overall
11
David Thornton
Dr. Chance
0.7
#8,236 overall
12
Michael Chow
Dr. Chow
0.4
#11,846 overall
13
Sofia Vassilieva
Kate Fitzgerald
0.3
#13,738 overall
14
Thomas Dekker
Taylor Ambrose
0.3
#14,339 overall
15
Marcos A. Ferraez
EMT
0.3
#16,118 overall
16
Evan Ellingson
Jesse Fitzgerald
0.2
#20,274 overall
17
Heather Wahlquist
Aunt Kelly
0.1
#26,300 overall
18
Ellia English
Nurse Alice
0.1
#28,851 overall
19
Nicole Marie Lenz
Gloria
0.0
#45,746 overall
20
Annie Wood
Uncle Tommy's Wife
0.0
#55,285 overall
21
Frank Cassavetes
Gus
—
22
Chris Kinkade
Dr. Nguyen
—
23
Jeffrey Markle
Dr. Wayne
—
24
Frank Peluso
Bailiff #2
—
25
Rico Simonini
Process Server
—
26
Keith Kraft
Paramedic (uncredited)
—
27
Nina Barry
Miss Swearingen
—
28
Paul Butler
Jesse age 3
—
29
Walter Raney
Pawn Shop Proprietor
—
30
John DeRosa
EMT
—
31
Noni Tulk-Perna
Ellen
—
32
Matthew Barry
Uncle Tommy
—
33
David Bortolucci
Harry
—
34
Andrew Schaff
Nurse Stephen
—
35
Mimi Fletcher
De Salvo's Secretary
—
36
Kaleti Williams
Bouncer (uncredited)
—
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